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                    Leaders of Research Groups
                    Prof. Dr. HUANG Xuenian


                    Professor,Vice director of Center, Leader of Filamentous fungi Synthetic Biotechnology Group

                    2020-present, Professor,

                    Qingdao Institute of Bioenergy and Bioprocess Technology CAS;

                    2015-2020, Associate professor,

                    Qingdao Institute of Bioenergy and Bioprocess Technology CAS;

                    2012-2015, Assistant professor,

                    Qingdao Institute of Bioenergy and Bioprocess Technology CAS;

                    2010-2012, Research assistant,

                    Qingdao Institute of Bioenergy and Bioprocess Technology CAS;

                    Research Interests:

                    Synthetic biology of filamentous fungi, including genome mining of fungal natural products, metabolic engineering of industrial strains for the efficient production of important pharmaceutical and bio-based chemicals.

                    1、Xuenian Huang, Ping Men, Shen Tang, Xuefeng Lu*, Aspergillus terreus as an industrial filamentous fungus for pharmaceutical biotechnology, Current Opinion in Biotechnology, 2021, 69:273-280

                    2、Xuenian Huang#, Wei Zhang#, Shen Tang#, Suhui Wei, Xuefeng Lu*, Collaborative biosynthesis of a class of bioactive azaphilones by two separate gene clusters containing four PKS/NRPSs with transcriptional crosstalk in fungi, Angewandte Chemie Int Ed, 2020, 2020, 132: 4379-4383

                    3、Shen Tang#, Wei Zhang#, Zhimin Li, Hongcheng Li, Ce Geng, Xuenian Huang*, Xuefeng Lu*, Discovery and characterization of a PKS/NRPSHybrid in Aspergillus terreus by genome mining, Journal of Natural Products, 83: 473-480

                    4、Xuenian Huang, Shen Tang, Linghui Zheng, Yun Teng, Yong Yang, Jinwei Zhu, Xuefeng Lu*, (2019) Construction of an efficient and robust Aspergillus terreus cell factory for monacolin J production. ACS Synthetic Biology, 8:818-825

                    5、Xuenian Huang, Yajing Liang, Yong Yang, Xuefeng Lu*, (2017) Single-step production of the simvastatin precursor monacolin J by engineering of an industrial strain of Aspergillus terreus, Metabolic Engineering, 42: 109-114


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