藍細菌是極具潛力的微生物光合平臺。相比高等植物和真核微藻，藍細菌具有更高的光合效率、更簡單的細胞結構、更短的生命周期、更便捷的遺傳操作體系，因此更適宜作為光合細胞工廠的開發底盤。以藍細菌為底盤，構建高效能光驅固碳細胞工廠，直接將太陽能和二氧化碳轉化為生物制品的光合生物制造技術，能夠在進行綠色生物合成的同時起到固碳減排的效果。
微生物制造工程中心長期聚焦藍細菌合成生物學和光合生物制造技術，通過重要藍細菌的遺傳操作平臺的完善、具有優良工程效能的藍細菌底盤藻株的篩選以及新型藍細菌代謝工程策略的開發，成功實現了對藍細菌光合代謝網絡的有效重塑，打通了乙醇、乙烯、葡萄糖、海藻糖、蔗糖、脂肪醇、脂肪烴等一系列產品的光驅固碳合成路線，并以工程化應用為目標進行了多項驗證性技術示范。相關成果獲山東省自然科學二等獎。
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