從事微生物分子生理學與合成生物學方向的研究，基本科研思路是通過新方法、新策略的開發應用來認識微生物細胞在脅迫應對和生物合成過程中的分子生理學機制，優化菌株生理和代謝功能，提高細胞工廠在生物煉制和光合生物制造過程中的整體效能。入選中國科學院青年創新促進會、研究所“清源學者-青年人才”計劃、中科院特聘研究骨干、山東省人才計劃。
2004/09-2008/06，山東大學生命科學學院，生物技術專業，獲理學學士學位
2008/09-2014/06，中國科學院微生物研究所，微生物學專業，獲理學博士學位
2014/07-2016/06，中國科學院青島生物能源與過程研究所，博士后
2016/07-2016/12，中國科學院青島生物能源與過程研究所，助理研究員
2016/12-2021/12，中國科學院青島生物能源與過程研究所，副研究員
2021/12-至今，中國科學院青島生物能源與過程研究所，研究員
2020/08-至今，中國科學院青島生物能源與過程研究所，微生物制造工程中心副主任、藍細菌合成生物技術研究組組長
社會任職情況:
擔任GCB Bioenergy期刊編委、Frontiers in Microbiology及Frontiers in Bioengineering and Biotechnology期刊Guest Associate Editor
主持項目情況:
作為負責人，主持國家自然科學基金（4項）、國家重點研發計劃課題、道達爾公司合作研發項目等十余項各類項目
國家自然科學基金面上項目，調控細胞形態以優化藍細菌光合固碳效率的策略開發及生理影響研究，32270103，2023-2026
國家自然科學基金面上項目，基于ATP合成酶擾動策略的藍細菌高溫高光耐受性改造和機制研究，32070084，2021-2024
國家自然科學基金面上項目，基因組復制工程輔助的連續進化技術提高藍細菌高pH耐受性的研究，31770092，2018-2021
國家自然科學基金青年基金項目，藍細菌能量-還原力代謝重平衡新策略及其生理影響研究，31600034，2017-2019
法國道達爾集團企業委托研發項目，改造光合微生物以提升細胞生長速度、固碳能力以及中鏈烯烴的合成，2020-2021
潔凈能源創新研究院合作基金，第二代微生物組生物光伏關鍵技術研究，29DNL202014, 2021-2023
代表性論著：
1. Zhang, S.#, Sun, J.#, Feng, D., Sun, H., Cui, J., Zeng, X., Wu, Y., Luan, G.*, Lu, X.*,(2023) Unlocking the potentials of cyanobacterial photosynthesis for directly converting carbon dioxide into glucose. Nature Communications,14, 3425.
2.Sun, H.#, Luan, G. *#, Ma, Y., Lou, W., Chen, R., Feng, D., Zhang, S., Sun, J., Lu, X.*, (2023) Engineered hypermutation adapts cyanobacterial photosynthesis to combined high light and high temperature stress. Nature Communications, 14, 1238.
3.Zhu, H., Xu, L, Luan, G., Zhan, T., Kang, Z., Li, C., Lu, X.*, Zhang, X.*, Zhu, Z.*, Zhang, Y.*, Li, Y.* (2022) A miniaturized bionic ocean-battery mimicking the structure of marine microbial ecosystems. Nature Communications, 13, 5608.
4.Luan, G., Lu, X.*, (2018) Tailoring cyanobacterial cell factory for improved industrial properties. Biotechnology Advances, 36(2):430-442.
5.Luan, G.*, Zhang, S., Wang, M., Lu, X.*, (2019) Progress and perspective on cyanobacteria glycogen metabolism engineering. Biotechnology Advances, 37(5):771-786; IF2022=17.68.
6.Luan, G., Cai, Z.*, Gong, F., Dong, H., Lin, Z., Zhang, Y. and Li, Y.*, (2013) Developing controllable hypermutable Clostridium cells through manipulating its methyl-directed mismatch repair system. Protein & Cell, 4, 854-8623.
7.Luan, G.#, Zhang#, S., Lu, X.*, (2019) Engineering cyanobacteria chassis cells toward more efficient photosynthesis. Current Opinion in Biotechnology, 62:1-6.
8.Luan, G., Cai, Z.*, Li, Y.* and Ma, Y., (2013) Genome replication engineering assisted continuous evolution (GREACE) to improve microbial tolerance for biofuels production. Biotechnology for Biofuels, 6:137.
9.Luan, G.#, Qi, Y.#, Wang, M., Li, Z., Duan, Y., Tan, X., and Lu, X.*, (2015) Combinatory strategy for characterizing and understanding the ethanol synthesis pathway in cyanobacteria cell factories. Biotechnology for Biofuels, 8, 184.
10.Zhu, Z., Luan, G.*, Tan, X., Zhang, H., and Lu, X.*, (2017) Rescuing ethanol photosynthetic production of cyanobacteria in non-sterilized outdoor cultivations with a bicarbonate-based pH-rising strategy. Biotechnology for Biofuels, 10:93.
11.Zhang, M., Luo, Q., Sun, H., Fritze, J., Luan, G.*, Lu, X.*, (2022) Engineering a controllable targeted protein degradation system and a derived OR-GATE-Type inducible gene expression system in Synechococcus elongatus PCC 7942. ACS Synthetic Biology, 11:125-134. IF2022=5.25.
12.Luan, G.#, Bao, G.#, Lin, Z., Li, Y., Chen, Z., Li, Y., Cai, Z.*, (2015) Comparative genome analysis of a thermotolerant Escherichia coli obtained by Genome Replication Engineering Assisted Continuous Evolution (GREACE) and its parent strain provides new understanding of microbial heat tolerance. New Biotechnology, 32(6):732-738.
13. Luan, G.#, Dong, H.#, Zhang, T., Lin Z., Zhang, Y., Li, Y., Cai, Z.*, (2014) Engineering cellular robustness of microbes by introducing the GroESL chaperonins from extremophilic bacteria. Journal of Biotechnology, 178, 38-40.
14. Wang, M., Luan, G.*, Lu, X.*, (2019) Systematic identification of a neutral site on chromosome of Synechococcus sp. PCC7002, a promising photosynthetic chassis strain. Journal of Biotechnology, 295:37-40.
15. Wang, M., Luan, G.*, Lu, X.*, (2020) Engineering ethanol production in a marine cyanobacterium Synechococcus sp. PCC7002 through simultaneously removing glycogen synthesis genes and introducing ethanolgenic cassettes. Journal of Biotechnology, 317:1-4.
聯系方式：
luangd@qibebt.ac.cn
